Depends. IMO, and understand I did not do what I am suggesting, to my disadvantage, I would spend down the taxable account earnings and and the principle and try to have it pretty well depleted when the RMD's hit (age 70.5) and/or SS Benefits (age 62-70). We are on the verge of RMD's (actually DW starts this year). I find the impact of taxable account interest is pretty stiff when coupled with the RMD (which in fact becomes a fully taxable account) and the impact on SS being taxable is also pretty stiff. Starting this year 85% of SS will be taxable and there is no reasonable way out of it. If we had "spent down" or depleted the taxable accounts before this year the tax impact would have been considerably less, somewhere in the range of 30% less taxes. Additionally, I should have put more into ROTH accounts, which I did, but early on I could have put more in them. In any event staying in the 15% tax bracket becomes harder and harder and spending down the taxable money is the only reasonable recourse.