The tuner's website usually has all the information on the tune's capabilities and any other changes/additions required to run the mapping. They also have dyno curves available to look at based on the tune and equipment on the car or after installed.
For my tune in my diesel, I had to put in a larger turbo, intercooler with more capacity, a 3 Bar MAP sensor, larger injector nozzles, some new intake plumbing and it was set to go. I increased my HP and Torque by about 50% over stock while maintaining about the same driveability and fuel mileage.
No internals needed to be changed in the engine. The next tune stage would have required forged connecting rods though.
I installed a Malone tune (out of Canada) and bought the upgraded parts from Kerma out of Colorado.