It's a complicated equation. "Quality of life" includes the cost of living, closeness or distance to amenities that are important to you, distance from family if that is important and so on.
When we retired, for DW being within an hour of her father and brother was a prime consideration, and mine was being out of the DC area traffic. So WV fit, although it was not perfect (I'd prefer to never see snow again) but her family is an easy 35 minute drive at any time of day, the grocery stores are 10-15 minutes away, as is medical care. And really, we only have to think about snow for two or three months of the year so I suppose that's endurable.
I heard the call to do nothing. So I answered it.