No experience with knee-joint synovial fluid (nor do I want any experience!), but I do have experience with abused finger-joint synovial fluid.
Some years ago we had a big ice storm. Trees damaged and breaking all over. I was doing clean up work on a couple of our trees using an extra heavy-duty fiberglass step ladder, and a chain saw. Being up on that particular ladder it is solid like the Rock of Gibraltar, but I think it weighs about the same! The ladder steps are made of aluminum C-channel, with the "C" facing down. I tended to carry and reposition the ladder with it open, using my left hand to lift the step side, the heaviest side, by reaching around the side rail, hand under the front of a step. The bottom fin of the C-channel is less than 1/8" thick, pointing down. This thin edge was exerting a great amount of pressure on my finger joints where fingers meet palm. I had leather gloves on most of the time.
My hand really started to hurt after a couple hours of work, including holding the cross handle on the chainsaw. I figured I must be getting a blister across two fingers there. Towards the end, I pulled off the glove to look... no blisters! But boy did it ache in the joints on two fingers. Within hours, I developed a solid lump on each of those two fingers, just up the finger from the palm. Doing some internet medical research, I seem to have stressed the joints badly, forcing synovial fluid out into adjacent tissue.
For a few weeks those two joints were very sore, like I had arthritis. And the two lumps were hard and tender. I avoided lifting much of anything with that hand for a month. I'm not a doctor, and I haven't stayed in a Holiday Inn for a long time, but my guess is: The loss of synovial fluid in the joints created joint pain due to lack of lubrication and isolation. Eventually, I assume that the body made more fluid and re-floated the joints, as the joint pain went away. And over a longer period of time, maybe 6 months, the body tissues finally absorbed and broke down the synovial fluid were it wasn't supposed to be.
I permanently fixed the ladder issue by riveting on some aluminum right-angle channel to the back side of the offending step's C-channel front fin, effectively widening the lifting area by a factor of >10!