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Old 09-02-2013, 10:16 AM   #21
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Originally Posted by grasshopper View Post
I use red rice yeast, kept my numbers OK, some muscle pain, mostly in the evening. I also get jimmy leg and take magnesium, sometimes helps. I lost 30 lbs first time in 30 years I have been under 24 bmi. I won't be tested again until December, maybe I will stop the statins. I have read that statins help inflammation, which may help keep my prostate in check.
Red yeast rice comes in two varieties. The ones on the shelf in pharmacies, which have absolutely no efficacy, and the ones you can order online from countries without regulatory bodies like the FDA, which can be very dangerous.
Just my two cents.
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Old 09-02-2013, 11:55 AM   #22
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I just read it, and agree that it is very interesting. One thing I wonder about-how can some genetic variant be most pronounced in America, if the next most affected population is Europe? Genetically, America is just Europe, with a lot of other strains added. He didn't mention that this genotype is quite variable from European country to country, which it seems would be the only other logical explanation for the pattern Graveline mentions.

Ha
One would think that this genotype is more prevalent in the poor areas of Europe that provided plenty of immigrants into the the USA during the 19th and 20th Century. Ireland comes to mind along with areas of Italy and up North to Sweden.

The other thing that comes to mind is, IIRC, genes can be turned on and off. Perhaps we are eating something that turns these genes on? None of this stuff is easy. If it was every Tom, Dick and Jane would be giving health advise.
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Old 09-02-2013, 12:10 PM   #23
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The study did not say proper exercise is of no benefit, but suggested its findings along with a small but increasing number of other studies, that statins may reduce the benefits associated with exercise.
Study quote from the link-
"The unmedicated volunteers improved their aerobic fitness significantly after three months of exercise, by more than 10 percent on average. But the volunteers taking the statins gained barely 1 percent on average in their fitness, and some possessed less aerobic capacity at the end of the study than at its start."

"But in the volunteers taking statins, enzyme levels related to mitochondrial health fell by about 4.5 percent over the course of the experiment. The same levels increased by 13 percent in the group not taking the drug."

IOW- In folks taking statins, the study found no significant benefit from the exercise program in it's endpoints- aerobic fitness and activity of an aerobic muscle enzyme. This study was not designed to look at other possible benefits of exercise in statin users, like cardiac risk reduction etc., so IMHO the findings were perhaps not presented in proper context by the blogger.

FWIW- My personal experience does NOT agree with this study (i.e. no aerobic benefit with exercise). Over years on same statin dose my aerobic fitness (e.g. 5k run time) clearly improves with my exercise training cycles, and declines with breaks in training (e.g. Holiday travels & celebrations ). No guarantee I may not develop statin muscle issues in the future, but most info suggest prob I won't.
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Old 09-02-2013, 12:13 PM   #24
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None of this stuff is easy. If it was every Tom, Dick and Jane would be giving health advise.
They aren't?

Ha
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Old 09-02-2013, 12:30 PM   #25
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None of this stuff is easy.
+1

It's all about individual choices based upon existing incomplete (sometimes questionable quality) info.
YMMV.
Ya pays yer $ & takes yer chances.
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Old 09-02-2013, 12:40 PM   #26
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They aren't?

Ha

HA, Exactly my point. Lots of people with opinions, very few with the credentials and objectivity who are worth listening to .
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Old 09-02-2013, 01:08 PM   #27
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IOW- In folks taking statins, the study found no significant benefit from the exercise program in it's endpoints- aerobic fitness and activity of an aerobic muscle enzyme. This study was not designed to look at other possible benefits of exercise in statin users, like cardiac risk reduction etc., so IMHO the findings were perhaps not presented in proper context by the blogger.

FWIW- My personal experience does NOT agree with this study (i.e. no aerobic benefit with exercise). Over years on same statin dose my aerobic fitness (e.g. 5k run time) clearly improves with my exercise training cycles, and declines with breaks in training (e.g. Holiday travels & celebrations ). No guarantee I may not develop statin muscle issues in the future, but most info suggest prob I won't.
LOL, I guess your interpretation of what the study concluded is different than mine, but glad you are having success with your exercise program with or without statins.
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Old 09-02-2013, 01:19 PM   #28
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Just to prove how confusing this is, here is another article. This one claims statins may slow down the aging process:

Statins may slow human aging by protecting against telomere shortening | ScienceBlog.com
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Old 09-03-2013, 05:40 PM   #29
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Just to prove how confusing this is, here is another article. This one claims statins may slow down the aging process:

Statins may slow human aging by protecting against telomere shortening | ScienceBlog.com
My doctor a couple years ago was wanting me to take Lipitor for the sole protection against the "widow maker" as he said there is very little protection in this area for late 40s to mid 50s men. I declined. I liked your HDL/Trig. formula Chuckanut, if for nothing else it puts me in a good state with a ratio under 2. I know there are few simple cures for anything, but I swear my religious conviction to daily oatmeal, walnuts, and fresh strawberry concoction has made great changes in my numbers. HDL way up LDL and Tri's down, BP was creeping into the mid 120's is back to 116/79. On no meds at all exempt for COQ10 and Krill Oil. I think I have discovered the "fountain of middle age" at almost 50. The sad part is I am not doing all this for health, but for my wallet. I am a cheap bastard and don't want to waste my money on a bunch of prescription meds with a 5k deductible.
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Old 09-04-2013, 11:02 AM   #30
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Originally Posted by Chuckanut View Post
Just to prove how confusing this is, here is another article. This one claims statins may slow down the aging process:

Statins may slow human aging by protecting against telomere shortening | ScienceBlog.com
Quote:
The great thing about statins is that they reduce risks for cardiovascular disease significantly and are generally safe for most people.
Really?

I don't think the drug companies medical establishment will be happy until everyone is on statins...
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Old 09-04-2013, 11:35 AM   #31
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I guess I'm one of the lucky ones.....

My Dr. prescribed 20mg of Lovastatin taken daily along with 81mg aspirin. My total cholesterol level was slightly above 200 with a strong family history of arteriosclerosis and heart attack.

I've been following this regimen for for several years and it has not slowed me down at all. I consider myself very active and exercise daily at a pretty intense level. I haven't had any of the muscle aches or other side effects sometimes associated with the statins. I'm 52 yo now and my total cholesterol level is somewhere around 151. Just lucky.... I guess!
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Statins and memory loss
Old 10-03-2013, 12:22 PM   #32
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Statins and memory loss

For you rats out there- statins linked to memory impairment.
Commonly prescribed statin linked to memory impairment, study in rats suggests ? TG Daily
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Old 10-03-2013, 06:45 PM   #33
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For you rats out there- statins linked to memory impairment.
Commonly prescribed statin linked to memory impairment, study in rats suggests ? TG Daily
I started this thread and can't remember what its all about
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