A. An area bomb which fumigates the room as a whole is usually recommended as the first line of defense against bed bugs. As you may not be in a position to bug bomb your hotel room while traveling abroad (without offending the natives), the following uses for Permethrin may help:
Spray treat at least the upper surfaces of your mattress when you first arrive, with 0.5% Sawyer® Permethrin Insect Repellent. Permethrin pump sprays are preferred because they are not restricted for airline travel. Allow the mattress to dry and air out before using it. Cover with a clean sheet for sleeping; do not sleep directly on the treated mattress. If you are concerned about the pillows, uncover them and lightly spray treat them with Permethrin also, re-covering them before use. Use 0.5% Permethrin spray as a residual surface insecticide for cracks and crevices around the room, and as a light spray on stuffed furniture, carpeting, and other fabrics around your sleeping quarters, where bed bugs and other crawling insects may hide.
Some of the information on bed-bugs was extrapolated from Maine University's Pest Management's Fact Sheet on Bed-Bugs at
http://pmo.umext.maine.edu/factsht/bedbugs.htm.