Telly
Thinks s/he gets paid by the post
- Joined
- Feb 22, 2003
- Messages
- 2,395
Oral administration of phenylephrine as an oral decongestant.
FDA report is here (big report, maybe start at page 31 for those really interested):
https://www.fda.gov/media/171915/download
My conclusion - The studies provided years ago that showed the efficacy of phenylephrine were poorly done to useless.
Not a surprise to me at all!
Some years ago, Pseudoephedrine Hydrochloride (the original Sudafed, and others including generics using PH) were put behind the counter, with registration and per-month limits applied to obtain them. Because some were using them as a base stock to create illegal drugs, to feed America's insatiable appetite for illegal drugs.
I am surprised that the law was never repealed.
Anyway, at the time of this change, I tried Sudafed PE (many other companies came up with their own, using the same non-useful replacement chemical, phenylephrine). I found it had no effect what-so-ever on my sinus pressure-induced headaches. Original Sudafed worked, the replacement was totally useless.
So I signed up, showed ID, etc., stayed with a generic original Sudafed. Sometimes pharmacy would be out of them. I kept enough stock to cover that. I don't take them that often, but there are times when I really need them.
Today's news brought the announcement of the FDA report. Long time coming.
FDA report is here (big report, maybe start at page 31 for those really interested):
https://www.fda.gov/media/171915/download
My conclusion - The studies provided years ago that showed the efficacy of phenylephrine were poorly done to useless.
Not a surprise to me at all!
Some years ago, Pseudoephedrine Hydrochloride (the original Sudafed, and others including generics using PH) were put behind the counter, with registration and per-month limits applied to obtain them. Because some were using them as a base stock to create illegal drugs, to feed America's insatiable appetite for illegal drugs.
I am surprised that the law was never repealed.
Anyway, at the time of this change, I tried Sudafed PE (many other companies came up with their own, using the same non-useful replacement chemical, phenylephrine). I found it had no effect what-so-ever on my sinus pressure-induced headaches. Original Sudafed worked, the replacement was totally useless.
So I signed up, showed ID, etc., stayed with a generic original Sudafed. Sometimes pharmacy would be out of them. I kept enough stock to cover that. I don't take them that often, but there are times when I really need them.
Today's news brought the announcement of the FDA report. Long time coming.