Doesn't mean you made the wrong choice, or can't make a new career choice. New location and new job means you get to start at the bottom, at least for awhile. The question is, how long/hard do you want to work to get somewhere with a new career.
I struggle with a long term assignment, then coming back to your former job. I long for the days of more responsibility, more action, etc. but I don't miss the stress, or the drive, the unwinnable positions and having less control, and setting ourselves up for failure from the start. I missed the family, missed coworkers, both personally and professionally. So, it's easy to miss the con's, and remember just the pro's.
What are you going to regret more? Not getting back on the treadmill, or are you going to miss feeling of some productivity mixed in with the office politics, BS, etc. Part of it, to me, is just the "devil you don't know". If you're financially set, you can try something and move on, but then I just fall into that rut, constant movement or trying new things. Just depends on whether you see that as positive or negative.
Speaking of movie quotes, Slap Shot: The unemployed hockey players wife, was it? Thinking about getting a job:
Shirley Upton: "Johnny always says you can just drink so much and screw so much."
A person has to find something to do. There may be something you've specialized in, and like doing, you're good at, etc. Try to find a job doing that. It's good to hire engineers and project managers that missed their calling as accountants, for instance. Meticulous, numbers minded, hopefully good people skills, etc.
-CC