OP, we can only suggest from our experiences and opinions. Our rubber hit the road when we encountered serious health conditions. Work adds to stress, unless you love what you're doing and it doesn't sound like you do. In March 2011 I had major surgery due to cancer and DH was so fed up with the mega-corp world his health was in jeopardy. He walked away in June, 3 months after my surgery and we never looked back.
You have to decide your priorities. Financially, you're set. Healthcare? The cancer threat was looming large in our lives when we made the decision to RE. DH did get a nice severance package and COBRA tied us over until we signed up for ACA. Personally, we're healthier because we walked away. I think DH would have stroked or had a heart attack if he kept up the demanding pace of work.
"If you want to go fast, go alone. If you want to go far, go together.