Famed bio hacker has incurable disease

Gary Smith

Recycles dryer sheets
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Kentucky

One of the many youngsters I tangle with regularly on X. X skews young. The health/fitness/longevity influencers there are almost all under 60 years of age. They pontificate daily about living a long life yet haven’t a clue the pitfalls that await them in old age.

Brian is actually a good guy. But he is obsessive about ending aging, has a team of 30 around the clock doctors that monitors every health metric imaginable, and at one time was taking 111 supplements daily. He spends $2,000,000 annually to beat death. I have been hearing this song and dance about beating aging or living to 150 years old since the late 1970s. Most back then just like the ones now will be lucky to make it to 80, much less in good health. Brian is only 48 years old.
 
That’s really sad that he’s wasting so much time in his life just trying to live longer. It definitely sounds like an obsession and it’s sad that he has such a disease at such a young age.

I think our healthy habits can affect our quality of life, and sometimes our length of life, but from my observations of people, I think genetics seems to be the deciding factor, as well as if you get exposed to any chemical or environmental factors through your life that shorten it. Old age is indeed a gift that many people aren’t lucky enough to get.
 
Oh, but he has it figured out. He got the rare autoimmune disease from fast food and sugary drinks and cereal. A very common diet of many American kids then and now.
 
I remember learning about this guy and I'm sad that he has developed this disorder. Reading a little bit, it appears to be a mostly manageable disorder, unless untreated. Apparently there is a genetic component but also environmental. This is true of many things that have a genetic component -- it is no inevitable.

I did see he blamed his childhood diet and stress. But you have to wonder if up to 111 supplements a day and the disorder's association with B12 and iron deficiencies (exactly the primary issues with a vegan diet) played a role. ETA: I just read he had been taking high doses of rapamycin, an immune suppressing drug developed for organ rejection, in an effort to slow aging.
 
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Oh, but he has it figured out. He got the rare autoimmune disease from fast food and sugary drinks and cereal. A very common diet of many American kids then and now.

Agree-while that is a terrible diet, I don’t know if there is any evidence that it causes auto immune disease. It can certainly lead to other chronic diseases.
 
I just read he had been taking high doses of rapamycin, an immune suppressing drug developed for organ rejection, in an effort to slow aging.
I believe Peter Attia is another who takes rapamycin and has been very strongly promoting it. However, there are a lot of caveats involving dosing, and he has gone into that pretty deeply. I don't recall the specifics, but his website most likely has them.
 
I believe Peter Attia is another who takes rapamycin and has been very strongly promoting it. However, there are a lot of caveats involving dosing, and he has gone into that pretty deeply. I don't recall the specifics, but his website most likely has them.
In his book, Outlive, he spends time discussing it. His bottom line on longevity is exercise (lots of it), low stress living and a good diet. Nothing magic..
 
I admire the dedication of those people who make an avocation out of staying healthy, but I remain skeptical. My father's philosophy:
"I eat when I'm hungry, I drink when I'm dry
And if whiskey don't kill me, I'll live 'til I die."
:2funny:

Disclaimer: I've already lived longer than he did, so I can't recommend that approach.
 
I believe Peter Attia is another who takes rapamycin and has been very strongly promoting it. However, there are a lot of caveats involving dosing, and he has gone into that pretty deeply. I don't recall the specifics, but his website most likely has them.

There are other links showing rapamycin has questionable to zero value in humans. It is always something. Back in the 1970s and 80s it was gerovital. Hollywood stars and financial moguls were flying overseas for injections. Longevity protocols are more commercialized than ever with …………..
.whose sole purpose is to make a buck.

Edit: Brian Johnson was on rapamycin for five years before his medical team decided the side effects were too severe. Below is an excerpt from one of Brian’s posts on X (11/14/24) regarding the drug

>>>>>Additionally, on October 27th, a new pre-print [5] indicated that Rapamycin was one of a handful of supposed longevity interventions to cause an increase/acceleration of aging in humans across 16 epigenetic aging clocks. This type of evaluation is the first of its kind, as most longevity interventions up to date have been tested against one or two aging clocks, leading to invisible biases and potential intended “cherry picking” of favorable clocks for the tested interventions.<<<<<
 
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The best studies I've seen date back quite a ways and they used animal models. I recall that rodent life spans could be nearly doubled by very restrictive caloric intake (short of malnutrition).

I decided I'd eat more ice cream and die earlier. None of us gets out of here alive. Might as well enjoy what ever journey we have on Earth.
 
I haven't read up on this guy, but from what I gather on this thread, it sounds like he spent so much time trying to increase his life-span, that he wasn't taking time to enjoy the time he had.

Maybe I'm wrong, and at any rate, I wish the best for him.
 
The best studies I've seen date back quite a ways and they used animal models. I recall that rodent life spans could be nearly doubled by very restrictive caloric intake (short of malnutrition).

I decided I'd eat more ice cream and die earlier. None of us gets out of here alive. Might as well enjoy what ever journey we have on Earth.

The discussion of ice cream as a health benefit has made the rounds on many of the longevity discussion forums over the years. Invariably occasional posters will chime in how their grandparents ate ice cream daily and made it well into their 90s. My lady friend’s Dad made it to 94 in good health and ate a bowel before bed ever since she was a kid. In order to gain some weight I have added vanilla ice cream recently to my daily dietary regimen. So we shall see.

Edit: The real superfood full of nutrients and little sugar that has made the most impact on my health are 90% dark chocolate squares.
 
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I believe Peter Attia is another who takes rapamycin and has been very strongly promoting it. However, there are a lot of caveats involving dosing, and he has gone into that pretty deeply. I don't recall the specifics, but his website most likely has them.
Attia quit taking and doing a lot of things when the human evidence didn't pan-out, including rapamycin and metformin. That's one of Attia's strengths IMO, he changes his position based on evidence.
 
I haven't read up on this guy, but from what I gather on this thread, it sounds like he spent so much time trying to increase his life-span, that he wasn't taking time to enjoy the time he had.

Maybe I'm wrong, and at any rate, I wish the best for him.
It seems very sad. But some people have obsessions.
 
The first sight I looked up regarding autoimmune diseases states that about 4.6% of Americans have an autoimmune disease. The note that Bryan Johnson included in the site listed in Post 1 (above) says that 2 to 5% of people have the disease HE has! I question that but maybe it's correct.

In any case, while autoimmune diseases (in general) are not exactly common, they certainly are not rare. Most of them are treatable/manageable. I have one. My daughter has a different one. So far they are both treatable but either of our diseases COULD shorten our lives.

Trying to live much longer than average is not as simple as living healthy. You need a bit of luck as well (like not having an autoimmune disease).

Good luck to Bryan Johnson!
 
Two of my friends that recently died were very strict with their diets and rarely ate anything that was bad for them and they exercised every day.

I do exercise every day, but I also eat more of what I like even when I know it’s not good for me, but just not on a daily basis. I don’t think their extremely healthy diets did them any good.
 

One of the many youngsters I tangle with regularly on X. X skews young. The health/fitness/longevity influencers there are almost all under 60 years of age. They pontificate daily about living a long life yet haven’t a clue the pitfalls that await them in old age.

Brian is actually a good guy. But he is obsessive about ending aging, has a team of 30 around the clock doctors that monitors every health metric imaginable, and at one time was taking 111 supplements daily. He spends $2,000,000 annually to beat death. I have been hearing this song and dance about beating aging or living to 150 years old since the late 1970s. Most back then just like the ones now will be lucky to make it to 80, much less in good health. Brian is only 48 years old.
Most of these wellness influencers are trying to sell something. Sometimes they even believe their own hype.
 
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