Join Early Retirement Today
Reply
 
Thread Tools Search this Thread Display Modes
BPH and Avodart
Old 08-28-2007, 04:16 PM   #1
Recycles dryer sheets
 
Join Date: Apr 2006
Location: Hardscrabble Texas
Posts: 372
BPH and Avodart

Well, after recurring bouts with prostatitis my doctor has now diagnosed me with BPH (enlarged prostate) and has prescribed Avodart. Has anyone used this medication? Just wondering how well it worked and what, if any, side affects you may have had.
Before today he had me on Uroxartol which is a different sort of drug and gave no results. My PSA normally tests around 0.8, but was a 1.2 during today's visit. My urine test did show some infection so was also prescribed Levaquin which knocks the infection down, however the prostatitis seems to show back up within a year.
Any feedback would be greatly appreciated.
__________________

__________________
.....#.....
Poundkey is offline   Reply With Quote
Join the #1 Early Retirement and Financial Independence Forum Today - It's Totally Free!

Are you planning to be financially independent as early as possible so you can live life on your own terms? Discuss successful investing strategies, asset allocation models, tax strategies and other related topics in our online forum community. Our members range from young folks just starting their journey to financial independence, military retirees and even multimillionaires. No matter where you fit in you'll find that Early-Retirement.org is a great community to join. Best of all it's totally FREE!

You are currently viewing our boards as a guest so you have limited access to our community. Please take the time to register and you will gain a lot of great new features including; the ability to participate in discussions, network with our members, see fewer ads, upload photographs, create a retirement blog, send private messages and so much, much more!

Old 08-28-2007, 05:16 PM   #2
Moderator Emeritus
Rich_by_the_Bay's Avatar
 
Join Date: Feb 2006
Location: San Francisco
Posts: 8,827
Quote:
Originally Posted by Poundkey View Post
Well, after recurring bouts with prostatitis my doctor has now diagnosed me with BPH (enlarged prostate) and has prescribed Avodart. Has anyone used this medication? Just wondering how well it worked and what, if any, side affects you may have had.
Pound,

Symptoms from a benign enlarged prostate come in two types: those due to the physical pressure of the enlarged gland pushing on the surrounding organs and tubes, and those due to the fact that the involuntary muscles around and in the prostate and bladder can get "twitchy" which makes them clamp down during urination.

The "-sin" drugs like tamsulosin, alfuzosin (uroxatral) and doxazasin work against the latter. They truly do work with about a 60-70% reduction in symptoms (like urinary hesitancy, frequency, urgency). Side effects are minimal other than wooziness when you stand up quickly, especially shortly after taking them. That's why they are often given at bedtime.

Finasteride and dutasteride ("Avodart") work by messing with the effects of testosterone on the gland. After about 6 months it shrinks the gland. Decreased libido and ED are among the possible side effects. The increase hair growth for a lucky few. They also work with about a 20% improvement in symptoms on average. Their effects on the incidence of prostate cancer are under study - it is possible that they decrease the incidence but that those which break through are more aggressive.

It's also important to know that given anough time, about 50% of men with flare ups of prostate symptoms get better on their own with no treatment.

I'm pretty conservative with patients whose symptoms are mild, use the "-sin" drugs if necessary, and reserve the hormone manipulating drugs for more persistent or severe symptoms. If serious blockage, kidney problems or recurrent/severe infections arise, it's time to consider surgery. That seems to be less and less the case recently.

Hope this is helpful. Now read my signature line .
__________________

__________________
Rich
San Francisco Area
ESR'd March 2010. FIRE'd January 2011.

As if you didn't know..If the above message contains medical content, it's NOT intended as advice, and may not be accurate, applicable or sufficient. Don't rely on it for any purpose. Consult your own doctor for all medical advice.
Rich_by_the_Bay is offline   Reply With Quote
Old 08-28-2007, 05:25 PM   #3
Thinks s/he gets paid by the post
 
Join Date: Aug 2002
Posts: 1,322
I'm surprised you have an enlarged prostate with a PSA of only 1.2. Guess it shows that PSA can be difficult to figure. Mine has been on a yo yo in the high 2's and low 3s for a couple of years. Good luck with your meds.
__________________
FinallyRetired is offline   Reply With Quote
Old 08-28-2007, 08:14 PM   #4
Recycles dryer sheets
 
Join Date: Apr 2006
Location: Hardscrabble Texas
Posts: 372
Thanks very much for the replies. Rich, you sound like my doctor as far as starting with the least aggressive approach first. My symptoms were never what my doctor or I considered severe although we were both surprised when they returned so soon. I believe it was the persistence that made him opt to try Avodart. I would say "twitchy" best describes my problem along with urgency and a lingering burning sensation after urination. I have been on the uroxatral for about 7 months after an initial round of Levaquin. I will admit to missing a dose of Uroxatrol occasionally due to forgetfulness. I also experienced some wooziness as you described, but not enough to worry about.

Interesting that many men get better with no treatment. Are there treatments involved (as in diet, heat, ice packs etc)?.......or is it more a matter of just toughing it out?

Thank you again
__________________
.....#.....
Poundkey is offline   Reply With Quote
Old 08-28-2007, 11:10 PM   #5
Thinks s/he gets paid by the post
SecondCor521's Avatar
 
Join Date: Jun 2006
Location: Boise
Posts: 2,398
TMI alert.

I had CBP for about a decade, and would just encourage you to be persistent in treating the infection. Good urologists (I had a couple of bad ones before I found a good one) will tell you that prostate infections are very difficult to get rid of. I was on long term antibiotics (years and years, including many different antibiotics, including Levaquin). Pure cranberry juice (no sugar, no other juices mixed in) helps. Prostatic massage (Google this) will also help.

I don't know anything about BPH and PSA, but it sounds like you're not really getting rid of the infection, which can be, as I'm sure you know, very annoying.

2Cor521
__________________
"At times the world can seem an unfriendly and sinister place, but believe us when we say there is much more good in it than bad. All you have to do is look hard enough, and what might seem to be a series of unfortunate events, may in fact be the first steps of a journey." Violet Baudelaire.
SecondCor521 is online now   Reply With Quote
Old 08-29-2007, 08:31 AM   #6
Moderator Emeritus
Rich_by_the_Bay's Avatar
 
Join Date: Feb 2006
Location: San Francisco
Posts: 8,827
Quote:
Originally Posted by SecondCor521 View Post
...would just encourage you to be persistent in treating the infection ...Pure cranberry juice ... helps. Prostatic massage (Google this) will also help...like you're not really getting rid of the infection
Glad you found something that worked for you, 2Cor, but be careful with your well-meaning advice.

There are several different conditions potentially being alluded to here, each with a different set of causes, treatment and diagnosis alternatives - Acute prostatitis, Chronic bacterial prostatitis, Chronic prostatitis/pelvic pain syndrome, inflammatory, chronic prostatitis/pelvic pain syndrome, noninflammatory, and Asymptomatic inflammatory prostatitis. Your kind suggestions may not be appropriate or accurate for everyone.

I'm sure Pound will sort this out with his doctor - each situation is different.
__________________
Rich
San Francisco Area
ESR'd March 2010. FIRE'd January 2011.

As if you didn't know..If the above message contains medical content, it's NOT intended as advice, and may not be accurate, applicable or sufficient. Don't rely on it for any purpose. Consult your own doctor for all medical advice.
Rich_by_the_Bay is offline   Reply With Quote
Old 08-29-2007, 08:44 AM   #7
Thinks s/he gets paid by the post
SecondCor521's Avatar
 
Join Date: Jun 2006
Location: Boise
Posts: 2,398
RIT,

Yes, thank you. I understand that but my post did not make that clear.

To be clear to Poundkey, my entire post should just be understood to be my personal experience and to encourage you to be persistent with addressing the infection, which is just part of the picture. I would also encourage you to work with your "in real life" doctor as Rich suggests.

2Cor521
__________________
"At times the world can seem an unfriendly and sinister place, but believe us when we say there is much more good in it than bad. All you have to do is look hard enough, and what might seem to be a series of unfortunate events, may in fact be the first steps of a journey." Violet Baudelaire.
SecondCor521 is online now   Reply With Quote
Old 08-29-2007, 12:36 PM   #8
Recycles dryer sheets
 
Join Date: Apr 2006
Location: Hardscrabble Texas
Posts: 372
2Cor521..... I understand that this is your personal experience..... and it's other peoples experiences (like yours) that I'm interested in to try to better understand my own situation.
Rich's list of the many (7?) variations/possibilities is something I need to discuss with my doctor on my follow up in 4 weeks. He hasn't yet made a call (although he's prescribing meds for BPH) on one particular diagnosis. Reading through Rich's list I would be inclined to think Chronic bacterial prostatitis in my case as it always seems to start as an infection, coupled with enlargment, and followed by antibiotics. I've never had pelvic pain with this.
My doctor does what I would consider a very mild form of Prostatic massage before I go to the lab for urinalysis which, according to him would help any infection show up on the test.

Thanks again for the replies
__________________
.....#.....
Poundkey is offline   Reply With Quote
Old 08-30-2007, 04:38 PM   #9
Thinks s/he gets paid by the post
 
Join Date: Jul 2005
Posts: 3,862
I'm taking Flomax and Avodart. My PSA was more like 10. Avodart eased my symptoms and shrunk my prostate by 1/3 or so after a year, and my PSA was down to 4 or so. That's pretty much as promised. But I still need to take Flomax 3 times a week (down from once a day).

Unfortunately that high PSA was my first test, so I didn't have a baseline. I did have a biopsy. The first in-office one hurt like heck and they LOST THE SAMPLES!! No result from that one. I got a second biopsy with full anesthesia after that. They didn't lose anything, but I did have to go to the emergency room for a catheter after those two sodas they wanted me to drink wouldn't come back out. That was fun too. But no cancer at least. I hope they won't insist on doing biopsies once a year or something!

I got tinitus soon after the biopsies. Levaquin, which I had both times, has a bad rep on the internet. That was the only possible side effect I noticed from all of these drugs.

Dan
__________________
Animorph is offline   Reply With Quote
Old 08-30-2007, 05:19 PM   #10
Recycles dryer sheets
 
Join Date: Apr 2006
Location: Hardscrabble Texas
Posts: 372
Thanks for sharing your experience Dan. Gosh, sounds like you had a miserable time with the procedures. I think I'd be a wreck after going through what you did.
I've had no side effects with Levaquin. My doc asked me to take the full dose of Levaquin (21 days) plus one per day of both uroxatral and avodart until my follow up. It's been less that a week now and I already notice a change for the better. Probably the antibiotic knocking the infection down.
Thanks again...... hope you are feeling better.
__________________
.....#.....
Poundkey is offline   Reply With Quote
Old 08-30-2007, 06:18 PM   #11
Thinks s/he gets paid by the post
 
Join Date: Sep 2006
Posts: 1,316
I have been on Proscar which is another brand similar to Avodart for about three months now. I was on uroxatral for a few months before but discontinued it due to decreased libido and mild ED. These side effects are all gone since I stopped the uroxatral (DW doesn't seem to mind).

According to my physician I had a benign prostate enlargement which was causing frequent urinations but no pain or burning sensation and my PSA tests for the last five years have been normal.

My symptoms have improved but I have to keep a close eye on it since my older brother had his prostate surgically removed last November due to cancer.
__________________
Corporateburnout is offline   Reply With Quote
Old 08-30-2007, 08:50 PM   #12
Recycles dryer sheets
 
Join Date: Apr 2006
Location: Hardscrabble Texas
Posts: 372
Quote:
Originally Posted by Corporateburnout View Post
I have been on Proscar which is another brand similar to Avodart for about three months now. I was on uroxatral for a few months before but discontinued it due to decreased libido and mild ED. These side effects are all gone since I stopped the uroxatral (DW doesn't seem to mind).

According to my physician I had a benign prostate enlargement which was causing frequent urinations but no pain or burning sensation and my PSA tests for the last five years have been normal.

My symptoms have improved but I have to keep a close eye on it since my older brother had his prostate surgically removed last November due to cancer.
Interesting how these drugs effect people in different ways. At my age (59 tomorrow) decreased libido and mild ED may be somewhat normal. I didn't notice any marked difference in libido after 7 months of uroxatral.....although, as I said earlier, I would forget a dose here and there.
Actually my doctor said it would be the Avodart that would likely cause ED and libido problems.

Thanks for your reply
__________________
.....#.....
Poundkey is offline   Reply With Quote
Old 09-28-2007, 02:25 PM   #13
Recycles dryer sheets
 
Join Date: Apr 2006
Location: Hardscrabble Texas
Posts: 372
Just wanted to post a follow up about my one month check up with my doctor. I took the Levequin for the first 21 days, and have been on Uroxatral and Avodart for about a month. My urine test showed no infection at all.....doc used the words "clear as water". My PSA which had gone from my normal 0.8 to 1.2 has now dropped down to 0.6. Doc says my prostate is reduced in size by about 10% so far, but is now firm and not "mushy" (again, his words). So....things look good. No side affects from the meds yet, but he wants me to stay on both uroxatral and avodart for a full 6 months then check back....so we'll see.
Thanks again for all the input
__________________

__________________
.....#.....
Poundkey is offline   Reply With Quote
Reply


Currently Active Users Viewing This Thread: 1 (0 members and 1 guests)
 
Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are Off
Pingbacks are Off
Refbacks are Off


 

 
All times are GMT -6. The time now is 08:23 PM.
 
Powered by vBulletin® Version 3.8.8 Beta 1
Copyright ©2000 - 2017, vBulletin Solutions, Inc.