Yesterday, DW and I attended a lecture on Nutrition. Part of the discussion concerned the subject of pharmaceuticals and introduced a term that was unknown to me. NNT = "number needed to treat".
Since then, I've spent several hours reading about and trying to understand the implications for our own healthcare. At first I was dismissive of the subject because I haven't seen it in headlines, but after some initial study, I'm not so sure.
Rather than trying to explain, I thought to throw the subject out to the forum, for viewpoints from those who have more expertise. In any case, a topic worth knowing about, particularly in light of the number of new drugs on the market, the recalls that have been made, and the warnings that have become obligatory in drug advertisements.
In short, NNT has to do with the mathmatically proven efficacy of different mediucines. A good place to start, is this 2008 article from Business Week, which is primarily directed to cholesterol medications, but gives a very broad overview towards to all phamaceuticals.
Do Cholesterol Drugs Do Any Good? - Businessweek
I'd wrap it up, very simply with this statement:
Drugs "do things that have effects", but do they help us live longer?
If the general tone of the article interests you, you may want to go to WIKI for more information... The article is deep into statistics and technicalities, but the bibliograpies at the bottom of the article go to specific studies that are enlightening to say the least.
Number needed to treat - Wikipedia, the free encyclopedia A companion wiki article is NNH...
My jury is still out, but weighing my experiences with Lipitor and Avandia, and DW's experience with Fosomax and Prolia, I am looking at the risk/reward factors. NNT appears to give a good indication of how much we can expect in terms of extending out life term. At the very least, it seems that the subject will take us a step beyond our doctor's recommendations.
Since then, I've spent several hours reading about and trying to understand the implications for our own healthcare. At first I was dismissive of the subject because I haven't seen it in headlines, but after some initial study, I'm not so sure.
Rather than trying to explain, I thought to throw the subject out to the forum, for viewpoints from those who have more expertise. In any case, a topic worth knowing about, particularly in light of the number of new drugs on the market, the recalls that have been made, and the warnings that have become obligatory in drug advertisements.
In short, NNT has to do with the mathmatically proven efficacy of different mediucines. A good place to start, is this 2008 article from Business Week, which is primarily directed to cholesterol medications, but gives a very broad overview towards to all phamaceuticals.
Do Cholesterol Drugs Do Any Good? - Businessweek
I'd wrap it up, very simply with this statement:
Drugs "do things that have effects", but do they help us live longer?
If the general tone of the article interests you, you may want to go to WIKI for more information... The article is deep into statistics and technicalities, but the bibliograpies at the bottom of the article go to specific studies that are enlightening to say the least.
Number needed to treat - Wikipedia, the free encyclopedia A companion wiki article is NNH...
My jury is still out, but weighing my experiences with Lipitor and Avandia, and DW's experience with Fosomax and Prolia, I am looking at the risk/reward factors. NNT appears to give a good indication of how much we can expect in terms of extending out life term. At the very least, it seems that the subject will take us a step beyond our doctor's recommendations.
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