I had a completely drug free colonoscopy. The anesthesiologist sat in the corner reading a book the entire time! It was not painful at all, with just a minor amount of cramping. After the procedure, I hopped off the stretcher and walked home. No need for an escort. I carefully considered the risks of allergic reaction, respiratory problems, etc. from the sedation and decided that the risks or Propofol or Fentanyl outweigh any benefits. I also have not seen any research that indicates there is a higher risk of traumatic injuries during a colonoscopy with patients who are awake. (I have actually read studies that Propofol administration is associated with an increased risk of perforation). Most people in other countries, like Europe, do not use sedation. Yet in the U.S. doctors are now using full anesthesia for the procedure. It is very profitable. I have two friends who are gastroenterologists, and both had drug free colonoscopies. Something to consider...especially for those who are sensitive to anesthesia.