1. Gluconeogenesis. I have found conflicting information exactly how much protein it takes to start converting it into carbs. One source says more than 12 hamburgers; it won't happen until the liver is so overloaded with protein that the normal process is swamped.
2. How long does it take to get back into ketosis after one insulin pulse? If it takes "days" as claimed in the Keto Dieting books, then Intermittant Fasting cannot work, because you only have at most 18 hours of fasting.
Which is telling a lie - the keto diet books or the intermittant fasting books?
3. How do you really know when you are in ketosis or insulin metabolism? Can you have a positive-for-ketosis ketosis number (from a breathalyzer, using acetone as a proxy for Beta-HydroxyButyrate) for some period of time even after an insulin pulse?
If you are willing to prick your finger to quantify insulin -- exactly what is the number that turns off ketosis? How fast does the switchover happen - minutes, or the by the end of the ~3 hour length of an insulin pulse?
Nothing I have read indicates that you can be in a blended state where your cells are taking in both sugar and lipids at the same time. And your liver is converting/releasing both at the same time. But the intake paths ARE different at the cellular level...
If the liver is an either/or switch, then sugar might compete with fat for entry into cells until the lipids in the blood are exhausted; I don't know if cells have a preference - I have not found any info about that. It would have to do with the metabolic cost of transporting each. If you have excess sugar + fat above in your blood above your metabolic needs, would insulin have fat cells
convert both to fat for the duration of the pulse? Therefore, exercise immediately after eating until the insulin pulse fades
I just blew a 7.9 on my KetoScan breathalyzer, and we are having chili for dinner, which has a good amount of carbs (no sugar added to the beans). I'll do it again afterwards a couple of times. But I'm kind of hungry now, so I'll snack on a few ounces of Heavy Whipping Cream. A quart has 65g carbs.
4. People talk about being in "deep" ketosis, which means a high number. I don't see the relevence; if you are burning calories because you are exercising the number should rise, and when sedentary fall. Nobody talks about learning your "resting" keto number; why not?
5. I'd like to see a scale converting a keto breathalyzer number into calories/minute being burned. Would need to factor in your lean weight... Surely that is done by the lab/medical treadmill test machines?
6. I have read that the urine strips for keto are not useful once you are "in" keto, because they measure a waste product produced during the transition and not so much when in steady-state. Or something like that.
7. Getting to 70-80% fat is mathematically difficult. Meat and hard cheese don't seem to have more that 55%, maybe 60% fat, and you need to eat all the bacon grease from the pan to get there*. A tablespoon of MCT oil in your coffee is not nearly enough to make up that remaining 20-25% fat.
At 1600 Kcal, you get 800 fat + 800 protein in your meat/cheese, then add 400 pure fat; its only 60% fat total (12/20). At 55% fat, it adds up to 64% fat. And I need lots of roughage (not soluble) to keep fat in my gut long enough to be absorbed and not expelled (GERD issue).
* Which is hard to do without bread. The fake bread is not very absorbent, and most taste & have a mouth feel like cardboard.