In the months after the Pfizer and Moderna vaccines arrived, I have been thinking of a hypothesis. Before anyone hammers at me, remember the definition of "hypothesis".
Here it is... Covid-19 may be the first appearance of a "Catalyst Virus" (I made up the moniker). In a nutshell, IF it turns out that the damage done to the body from a Covid-19 infection is a result of an immunological system overreaction to the virus, in effect, the virus does not directly damage/kill, but a person's particular body's overreaction to the virus does. With this, "Immunological System" should not be looked at as some body-global effect, as in "I have a good Immunological System". Instead, immune system on a per-body basis would be much more nuanced, can not make global statements about a particular body.
If this hypothesis eventually proves to be true, can a predictor be derived via who had more reaction to a Covid-19 vaccine? Instead of a common positive "If I have a reaction to the vaccine, that's ok, I must have a robust immune system" thinking, could it be the reverse? Could those, like DW and I, who had zero effects from the Pfizer vaccine doses, have been the least likely to have ended up in a hospital on a ventilator, or deceased? And those who had relatively strong reaction(s) from a Covid-19 vaccine have been the most likely to be a statistic, if they had not been vaccinated?
It seems it would be a tough hypothesis to test! If an individual specitivity of sectors of immune system are assumed (and I don't know how "sectors" are defined, probably something different than now), then it would seem that clones would be needed, one to get the vaccine, the other, to not!
Remember, it's a hypothesis.
EDIT: I would have preferred to start a new topic with this post, but figured it would be just merged into an existing Covid-19 topic anyway, so I might as well pick one.