We drive 600 miles from Chicago to far northwest Minnesota twice a year, spring and autumn, to our favorite walleye lake. Been doing it for many, many years. Decades ago, we'd leave in the early evening with our young son set up to sleep in the back seat and arrive the next morning about 12 hours later. Now in our 70's, we take two days to do the drive, about 450 miles the first day and 150 miles the next on the way up. On the way back, we've still been doing it in one long day since we have frozen fish with us.
We now have one of those fancy Yeti coolers and I'm confident that if I invest a few bux in dry ice, we can split the drive home into two or three days without worrying about the fish thawing. We're setting up plans to do that.
We just returned from two months camping in Florida. We took three days each way to do the 1,100 - 1,200 miles. The longest day was the first going down and the last coming back. You don't want to be camping anywhere north of Louisville in the winter! It'a likely to be cold and often hard to find open campgrounds.
