We stopped taking family vacations years before we stopped working...I'm talking about the ones with the MIL, FIL, BILs, SILs, and all of the kids. It was a good thing when all of the kids were young (ours are the youngest), but as the kids got older the family vacations lost a lot of appeal...especially to the kids. We began taking vacations that were more interesting to our kids. We declined a trip or two of the "family vacations", explaining that the kids wanted to go "here" or "there" instead. MIL and FIL were disappointed but understood about kids wanting more adventure in their trips. Eventually the "family vacations" sort of stopped happening.
After we pulled the plug: Sometimes, our kids ask us to join them for their spring break and summer vacations, and we do. We just drove from CA to TX for a Big Bend spring break with DS and family. So, I guess that we now take a few family trips...with our kids. Sometimes, we meet BIL and SIL for a day or two, but nothing that qualifies for a "family trip".
Guilt...what guilt?!