Galena is adorable. Lots of antique folks from the Chicago area--the rich antique dealers--have moved there. When I was taking care of my Mom I went there to shows a few times. You will love, love, love visiting. Everyone is friendly there and your food/hotel should not be very high either if you look around a little.
Another town to see is LeClaire, Iowa, down the street. My son moved there as he works in Davenport. Another adorable little quaint town (no chain stores and all old--so cute). If you watch "American Pickers" on cable tv they are from LeClaire, and they are situated in an area of the country (Iowa) where alot of those farmers have things stashed away in barns. No dummies are those two guys. Just FYI.
If you go that far wander over to the Quad Cities and have a buffet at one of the gambling boats or Jumer's which is now on land and has a hotel/gambling hall/buffets/entertainment/etc. Everything is cheaper there like Indiana, so you won't get ripped off. Enjoy!!!
And everyone is friendlier in these areas of the country, too. Lots of motels and food places there (chains that is), because everyone flies in to gamble and party there, so it isn't expensive at all to stay there.
It will take you probably 1-1/2+ hours to drive (I checked with Mapquest on this for you) from Galena thru LeClaire and to the fun in the Quad Cities. For a weekend trip--or even better a 3 day trip--you could have yourselves a ball on the cheap there.
By the way, if you time your trip you could take in a show with top name entertainment in the Quad Cities for less than half what I paid for a ticket in Houston if you time it right.
For years I avoided going back to this area here where I was raised, but in the past 7 years when I took care of my mother till she died back there I grew to really love the friendliness of the people and their kind, caring hearts.
This is such a great area of the country...truly. People still wave at you if you are on the front lawn, and I'm talking about my mother's neighborhood which was a Drs./lawyers/business owner's ghetto--not a farm area. It's amazing to me cause nobody ever did that in innercity Houston or Chicago. I loved it!