From what I understand, the reference ranges used by many labs are based on blood test results from lots of people who are judged to be generally healthy because they are not currently "symptomatic" for a particular condition. But just because someone is not symptomatic (at that particular moment) does not mean they are in optimum health, nor does it mean that they are not on the verge of having issues related to a particular blood test result. So.........someone could have a serum ferritin level of 400, and clearly be headed for problems down the road (maybe not far down the road?), but their result is lumped in with the other "normal" ferritin results to help calculate the desire reference range. Am I correct about that? If so, that means the desired reference ranges for things like ferritin are based on flawed data. That is probably why my ferritin result of 400 did not trigger a reaction from my PCP, when it clearly should have. Virtually all of the medical literature says that 400 is way too high, yet it was fine with my doctor, since it was within the reference range. It is insanity.......
I think it is highly unlikely that the resolution of my issues was not connected in any way to the reduction in serum ferritin I achieved through donating blood. Once I got my ferritin level down below 300, my symptoms improved markedly. Once I got it down below 200, they were basically gone. Obviously, it is a sample size of 1, but I am comfortable with concluding that my high ferritin level was the cause of my issues in this case.
DW and I have both had negative experiences with physicians, yes. I won't bore you with more long stories, but DW also had a lot of problems a few years back, and went to about 3 different doctors to try to figure out what was going on. Like my situation, none of them were able to help at all, so I started doing my own research to try to figure out what was going. After extensive reading, I concluded that she may have a Vitamin B12 deficiency, based on her symptoms. So, I suggested this to the 4th doctor she went to (only telling him I thought it might be a possibility, and asking if it would make sense to look further into it). Fortunately, that guy (a physician's assistant) took my comments seriously, did look into it, and concluded (after ruling out some other things) that she did indeed have a B12 deficiency, and also Pernicious Anemia. Now she takes B12 injections and is doing okay. So that was a positive experience in the end, but it seems like the bad experiences have outnumbered the good experiences lately, at least for us.