As has been mentioned, sadly NOLA has become infested with crime, especially against tourists. Wherever you go, don't stand out as a tourist, and never find yourself somewhere in the city center alone. The last time I was there in 2019 (Xmas to NYE) some Chinese tourists staying in the VRBO condo across the hall from me were kidnapped along Canal St, driven outside the city, robbed of everything and left by themselves in a swamp. Nice young couple but they were so terrified they left the city that day. I felt so bad for them.
My favorite restaurant in the city is Mandina's, also as others have mentioned. Best po boys in the city.
A few blocks from Mandina's is my favorite bar, Finn McCool's. It's a great, low-key, neighborhood dive bar. I always make new friends there.
Many restaurants near Lake Ponchatrain advertise great seafood; don't believe a word of it. Those are among the worst restaurants in the city, and highly overpriced.
But, yeah, sadly I think my trips to NOLA are in my rearview window at this point. Been there a dozen or more times over the last 35 years and the city has become so run-down and, post-Katrina, infected by major crime. Shortly before I was there in 2019 a Google van taking images for Streetview was carjacked in the Lower 9th ward. Imagine, carjackers stealing a vehicle that is loaded with cameras saving images instantly to the cloud. If they're willing to do that, they'll do anything to get what you have.