I haven't done those but I did carry DW(115#) and a backpack from the Napali Coast State Park back to the trailhead after she tore her hamstring back in 2009. I can't remember how many miles, but my right knee reminds me at least once a week.
I also carried about 45# of tools, instruments, battery, detectors on my mine belt each and everyday I spent in a coal mine for 35 years.