Thanks for all the suggestions please keep them coming.
After sleeping on it, I'm sure that UPENN has some safe way for the kids to transport between the hosipital and school. DD is tasked with finding the specific details on how that works logistically. We are going to insist on the self defense awareness class, as a condition of staying in the school. Good tip on the ear buds.
Someone mentioned Walnut & 16th. I think this is what originally brought the carelessness of our daughter with regard to her surroundings and personal safety. When my wife visited, and they got off 1 stop later that was a shorter walk to the campus, they had to walk past several groups of people hanging out on the street. It wasn't well lit, and my wife asked DD do you have the pepper spray? No was the reply.
I understand the common sense piece of safety.