72 Ford Pinto (used) - no major problems in 4 years, plenty of small ones
76 Saab 99 (used) - in rough shape when I got it, got worse (bad U-joint, clutch, probably more I can't remember), dumped it rather than put money into it
84 VW Rabbit GTI (new) - a pocket rocket, sold to a friend because my now ex-wife hated sitting in it, he drove it problem free for over 120K. She had an 80 T-bird, prayed it would make it to the out of town dealer when trading it in for the 89 Integra.
86 Saab - lots of problems, broke down on I-95 in DC when some cable to the fuel injection system came loose; spedometer way off; monthly trips to dealer for other work; unloaded after 1 year. Saab fooled me twice, shame on me.
86 Acura Integra (used) - my best car ever, fun to drive and no problems until I got broadsided with 133K miles.
89 Integra (new) - auto transmission never seemed smooth, wife's car, sold for a van (keeping the 86) when we started a family.
91 Toyota Previa - some transmission problems fixed under warranty but I learned to hate Toyota service during that experience; ex- got it in divorce, and she sold it soon after.
90 Acura Legend (used) - A/C problem, never 100% sure of it for some reason, sold for an SUV
97 Honda CRV (new) - underpowered 4 cylinder, only problem was a clogged radiator, shop couldn't figure out how it got that clogged but was fine afterwards. Kinda wish I'd have kept it for my daughter to drive a couple years later, but I needed something bigger for some mountain driving.
97 Miata (used) - Bought as a 2nd "fun" car. No problems at all, still have it, not that many miles on it, sits over the winter and drives great each spring
04 Honda Pilot (new) - no problems, still have it, great car only it's the only one I can't get the EPA numbers on without driving like an old lady.
So I haven't given American car makers much of a chance myself but watched family go through lots of problems, and I've had good-to-great luck through the years with the Honda family, so I'm not really motivated to switch. I do like the looks of the Mustang convertibles, but I can't see getting rid of a reliable and fun car for it.
My daughter and I looked for a lot of used American cars for her first, looking at that range where it's depreciated a lot but still in decent shape. Wound up finding that with a 2003 Mitsubishi Galant. Too early to rate.