Midpack
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Exec summary: If you rotate your tires and keep them properly inflated, though less likely, they can still wear out prematurely due to alignment issues. Have alignment checked (free!) every time you replace tires, or more often if possible. Might save yourself some expense.
Long version: I can't remember when I've ever checked or had an alignment issue on a car we've owned and Yahoo!Autos suggests (below) we shouldn't have to unless we hit something. Recently, our Toyota Camry wore out some Michelin tires at under 40K miles, they were warrantied for 60K. They were rotated every 5K miles and kept properly inflated so I could not figure it out. Tire shop checked tread wear and it seemed pretty even, 5/32"±1/32" all around. Talked to Michelin and they suggested my tread wear was uneven, one tire was 4/32", two at 5/32" and one at 6/32". Bought new tires and the dealer said we're going to check alignment for free, up to you if you want to pay for re-alignment. Alignment wasn't way out, but it was outside Toyota tolerances. Maybe we've been scammed, but it would explain why a reputable tire wore out on us prematurely since we thought we'd maintained them properly. I didn't pursue the warranty, it was clear talking to Michelin they were going to claim it was our fault due to uneven wear (and it is possible). So now we'll check alignment (for free) every time we get new tires, just to be sure. FWIW...
Long version: I can't remember when I've ever checked or had an alignment issue on a car we've owned and Yahoo!Autos suggests (below) we shouldn't have to unless we hit something. Recently, our Toyota Camry wore out some Michelin tires at under 40K miles, they were warrantied for 60K. They were rotated every 5K miles and kept properly inflated so I could not figure it out. Tire shop checked tread wear and it seemed pretty even, 5/32"±1/32" all around. Talked to Michelin and they suggested my tread wear was uneven, one tire was 4/32", two at 5/32" and one at 6/32". Bought new tires and the dealer said we're going to check alignment for free, up to you if you want to pay for re-alignment. Alignment wasn't way out, but it was outside Toyota tolerances. Maybe we've been scammed, but it would explain why a reputable tire wore out on us prematurely since we thought we'd maintained them properly. I didn't pursue the warranty, it was clear talking to Michelin they were going to claim it was our fault due to uneven wear (and it is possible). So now we'll check alignment (for free) every time we get new tires, just to be sure. FWIW...
If the wheels on your vehicle are correctly aligned when the vehicle is manufactured at the factory, they should not change alignment until something in the suspension wears out or is damaged. Alignment doesn't change. The only thing that changes it is wear or damage. Hitting a pot hole or a thousand pot holes won't knock your suspension out of alignment unless you hit something hard enough to actually bend metal. That really doesn't happen very often, so having the wheels aligned periodically is a waste of money.
It only takes a 1/8 inch of toe misalignment to drag the front tires sideways the equivalent of 28 feet for every mile traveled!